Fourth Hunnic-Sasanian War

The fourth Hunnic invasion of the Sasanian Empire was from 450-451 CE. It was a massive invasion, led by one massive army under Attila. The Huns first recaptured the wealthy city of Mithridatia and in 451, Attilas army clashed with the Sasanians at Antioch. However, Attila was overwhelmed by the heavy Sasanian Cataphracts. The battle resulted in heavy losses on both sides and Attilas army retreated. Shortly after, the Sasanians liberated and rebuilt Mithridatia.

Source
https://en.wikipedia.org/wiki/Huns#Under_Attila